As shown in Figure 2, after about 20–25 days from the inoculation, Control and uPAR rescue groups mice required sacrifice, due to excessive tumor dimensions, while we demonstrated significant growth inhibition in M6 A5 and HCT116 A3 and absolutely no growth in A375 PL1, confirming in vivo what we previously observed in vitro. This evidence concerns the gene PLAUR and neoplasm.