On the other hand, CD25 is expressed by the malignant cells of a number of cancers such as adult T-cell leukemia/lymphoma, cutaneous T-cell lymphomas, hairy cell leukemia, anaplastic large-cell lymphoma, granulocytic neoplasms and the Reed-Sternberg cells and associated polyclonal T cells in Hodgkin’s lymphoma. The gene discussed is IL2RA; the disease is cancer.