According to the ESC 2013 position statement, the diagnosis of acute myocarditis relies on a combination of a suggestive clinical presentation, first-line tests such as ECG, biomarkers including inflammatory markers, viral antibodies, serum cardiac antibodies, and cardiac biomarkers (Troponin I or T, BNP, or NT pro BNP), transthoracic echocardiography (TTE), and cMRI. This evidence concerns the gene NPPB and myocarditis.