Alu-Mediated EPCAM/MSH2 Cytoplasmic MSH2 Related to Genomic Deletions in the MSH2/EPCAM Genes in Colorectal Cancer Patients with Suspected Lynch Syndrome Rearrangement Is Responsible for Cytoplasmic Localization of MSH2 in LS Patients. This evidence concerns the gene EPCAM and Leigh syndrome.