ADAMTS13 and thrombotic thrombocytopenic purpura: TTP can be divided into two categories (1) more commonly seen acquired or autoimmune form (94.5% of cases⁠) and (2) very rare hereditary form (4.5% of cases⁠) caused by ADAMTS13 bi-allelic gene mutations also known as Upshaw-Schulman syndrome [5,6].