IL18 and rheumatoid arthritis: The most prominent difference was observed for IL-18 expressed by the median (max-min) p value in the AR [23150.0 (41548.0–46.8, p < 0.0001] and CG [17562.0 (24084.0–7944.0)], followed by IL-16 [539.1 (1919.1–7.8) p = 0.0491] and [449.4 (1664.6–7.8)], IL-31 [62.5 (27550.0–62.5) p = 0.0004] and [62.5 (10194.3–62.5)], and IL-32 [39.0 (14425.3–39.0) p < 0.0040] and [39.0 (115.0–39.0), all levels that were significantly higher in RA patients compared with controls (Figure 1).