Rao et al[14] in a real-world study of intravitreal injection of anti-VEGF drugs for the treatment of AMD in the US, based on data from the Intelligent Research in Sight (IRIS) registry, compared the one-year outcomes of the injections of bevacizumab, ranibizumab, and aflibercept. Here, VEGFA is linked to age-related macular degeneration.