We found that higher expression of C1QB, CEP55, HIST1H2BO, IFI6, KIAA0101, PBK, SPAG5, and SPP1 and lower expression of DCN, FZD7, KRT5, and TGFBR3 were associated with shorter overall survival time in breast cancer (Figure 5). The gene discussed is SPP1; the disease is breast carcinoma.