INS and polycystic ovary syndrome: Compared with the placebo group, PCOS patients treated with S. miltiorrhiza extract had significantly lower fasting blood glucose [MD = –0.25, 95% CI (–0.37, –0.13), P < 0.0001] and fasting insulin [MD = –1.16, 95% CI (–1.74, –0.58), P < 0.0001] (Figure 4).