AKT1 and atherosclerosis: The results of KEGG pathway enrichment analysis of CIF mainly involved vascular related pathways: cancer pathway, hepatitis B, fluid shear stress and atherosclerosis, PI3K Akt signaling pathway, measles, proteoglycans in cancer, MAPK signaling pathway, platinum resistance, relaxin signaling pathway, and NF-κB signaling pathway, including 20 important pathways as shown in Figure 5(b).