Studies have shown that c-myc is involved in the occurrence of multiple organ fibrosis, including renal fibrosis (Shen et al., 2017), PF (Yin et al., 2019), myocardial fibrosis (Zhang and Sun, 2019), lens fibrosis (Zhang et al., 2019), and liver fibrosis (Sharawy et al., 2018). This evidence concerns the gene MYC and Hepatic fibrosis.