LRBA and juvenile idiopathic arthritis: High consanguineous marriages in Arab countries provides an opportunity to find novel risk loci like LACC1 and LRBA that are associated with the monogenic juvenile idiopathic arthritis (JIA) and inflammatory bowel disease with combined immunodeficiency, respectively, in the Arab population (Alangari et al., 2012; Patel et al., 2014; Martorana et al., 2017).