CD4 and metastatic melanoma: The results of Kaplan–Meier analysis of 79 metastatic melanoma specimens (GSE54467) and a unique set of 51 treatment-naive primary melanoma samples (GSE98394) both indicated that higher fractions of CD4+ T, CD8+ T cells, and NK cells might be associated with better survival over those with low proportions (P <0.05; Figure 4).