Using serum samples from 88 patients and 37 healthy donors (HD), we first showed that serum BAFF levels (mean ± SD) measured at baseline were significantly higher in pemphigus patients than in HD (308 ± 13 pg/mL vs 252 ± 28 pg/mL, p=0.037) (Figure 1A). The gene discussed is TNFSF13B; the disease is pemphigus.