Pharmacological TNF inhibition with Etanercept, Infliximab and Adalimumab inhibits germinal center formation upon SRBC immunizationPharmacological TNF neutralization with Infliximab results in loss of mycobacterial infection resistance in M. tuberculosis infectionPharmacological TNF inhibition with Etanercept or Infliximab reduces transplantable tumor growth of MCA205 fibrosarcoma and MDSC accumulationPharmacological TNF neutralization with Infliximab protects mice from collagen antibody-induced arthritisExacerbated disease and decreased Treg numbers in EAE. Here, TNF is linked to fibrosarcoma.