A slight elevation (within triple of increase) of tumor markers, including Carbohydrate antigen199 (CA-199), Human Growth Hormone (HGH), Carcinoembryonic antigen (CEA), Cytokeratin-19-fragment (CYFRA21-1), squamous cell carcinoma antigen (SCC), pro-gastrin-releasing peptide (ProGRP), and neuron specific enolase (NSE), was observed. This evidence concerns the gene ENO2 and neoplasm.