As shown in Figure 2B, VPA/HPTA treatment alone significantly promoted an increase in the cell population expressing M1 marker (CD86; P <0.01) and M1 function markers (IL-12, IL-6, MHC-II, IFN-γ and TNF-α; P <0.01) at the transcriptional level in the tumor. The gene discussed is IFNG; the disease is neoplasm.