Similarly, the concentrations of CCL5 were compared between 800 T2DM patients and 884 controls, and it was found that these concentrations were higher in T2DM patients than in the controls (SMD=1.42; 95% CI: 0.56 - 2.29; Figure 1), but with significant heterogeneity (I2=98%). Here, CCL5 is linked to type 2 diabetes mellitus.