Additionally, CXCL10 concentrations were compared between 1,116 T2DM patients and 1,461 controls, and the results showed that the concentrations of CXCL10 were higher in patients with T2DM than the controls (SMD=0.87; 95% CI: 0.32 - 1.42; Figure 1), but with significant heterogeneity (I2=97%). This evidence concerns the gene CXCL10 and type 2 diabetes mellitus.