Considering CXC chemokines, concentrations of CXCL8 were compared between 1,405 T2DM patients and 1,599 controls, and the results indicated that T2DM patients had higher concentrations of CXCL8 than the controls (SMD=1.18; 95% CI: 0.64 - 1.72; Figure 1), but with significant heterogeneity (I2=97%). Here, CXCL8 is linked to type 2 diabetes mellitus.