Specifically, SARS-CoV-2 infection was shown to block autophagic flux by elevating GSK3β expression in lung cancer lines, or by depleting autophagy genes, such as SNAP29 (Synaptosomal-Associated Protein 29) along with lysosomal acidification genes in COVID-19 lung biopsy samples (Singh et al., 2020). This evidence concerns the gene SNAP29 and lung cancer.