In addition to the major virulence factors of meningitis-associated and uropathogenic E. coli (like P fimbriae adhesion cluster, K1 capsule, heme utilization systems, and the secreted autotransporter toxin), the strains showed VAGs typical for InPEC (especially the various bacterial secretion systems) underlining the clinical relevance of these pathogens. The gene discussed is KRT1; the disease is meningitis.