PRUNE2 and neoplasm: The serum level of iPTH was correlated with serum Ca (p<0.001, rs=0.685), alkaline phosphatase (ALP) (p<0.001, rs=0.802), phosphorus (P) (p<0.001, rs=-0.525) and tumor diameter (p<0.001, rs=0.570), as well as the expression levels of VDR (p=0.009, rs=-0.403) and PRUNE2 (p=0.009, rs=0.401) (Figure 4).