SELP and type 2 diabetes mellitus: Santilli et al. evaluated the effects of acarbose on markers of lipid peroxidation and platelet activation (8-iso-PG F2α, 11-dhTXB2, plasma CD40 ligand and P-selectin) in T2D patients; 20-weeks acarbose treatment induced a time-dependent reduction in markers of oxidative stress and platelet activation that followed a progressive improvement of postprandial glucose fluctuations and long-term glycemic control (Santilli et al., 2010).