SOCS2 is a member of the suppressor of cytokine signaling (SOCS) family and represses the cytokine-induced signaling transduction, thus inhibiting cancer progression (Ricobautista et al., 2006; Das et al., 2017; Chhabra et al., 2018; Tong et al., 2019). The gene discussed is SOCS2; the disease is cancer.