Age, Race, BMI, Albumin count, ECOG PS, ER/PR Status, Presence of Visceral Disease and Brain Metastasis, Arrhythmia, Coronary Artery Disease, Heart Failure, Hypertension, Cerebrovascular disease, Diabetes and Other Cardiovascular diseases, Prior treatment to anthracyclines, taxanes and trastuzumab. This evidence concerns the gene ALB and cardiovascular disorder.