IL1B and infection: In the case of severe infection, the viruses are sensed by monocytes, tissue macrophages, and resident dendritic cells, resulting in an uncontrolled pro-inflammatory cytokines (IFN, TNF‐α, IL‐1β, and IL‐6) production, leading to a phenomenon called a “cytokine storm”, which damages the respiratory epithelial cells of the host (Allegra et al., 2020).