INS and type 2 diabetes mellitus: To find the risk factors related to MCI in patients with T2DM, we first conducted simple logistic regression and incorporated the independent variables including age, gender, education level, BMI, hypertension duration, SBP, DBP, HbA1c, diabetes duration, history of smoking and drinking, FBG, 2h-PBG, TG, TC, LDL-c, HDL-c, use of insulin, genotype, and 24-OHC.