The previous report revealed that WDFY3-AS2 suppressed ovarian cancer progression by sponging miR-18a [26], WDFY3-AS2 may suppress the proliferation and invasion in oesophageal squamous cell carcinoma by regulating miR-2355-5p/SOCS2 axis [27], and WDFY3-AS2 also was reported to promote lung adenocarcinoma progression via targeting miR-491-5p/ZNF703 axis [28]. The gene discussed is WDFY3; the disease is lung adenocarcinoma.