Previous reports have suggested that XRCC2 is a target of microsatellite instability in medulloblastoma (Viana-Pereira 2009); however, no studies have revealed the expression pattern of XRCC2 in glioma, analyzed the correlation between XRCC2 and clinical features of glioma, or elucidated the impact of XRCC2 on the prognosis of glioma patients. The gene discussed is XRCC2; the disease is central nervous system cancer.