Bifurcation analysis was used to determine the relationship between the nociceptive neuron model and the antinociceptive effect that occurs during neuropathic pain suppression. The molecular mechanism of the bursting suppression was associated with the modification of the activation gating system of Nav1.8 channels by comenic acid, suggesting a possible molecular treatment for neuropathic pain. The gene discussed is SCN10A; the disease is neuropathic pain.