We also found significant correlation between ERBB2 mRNA and HER2 protein levels in brain metastasis (Spearman Cor = 0.697, P = 0.002), breast metastasis (Spearman Cor = 0.754, P = 0.002), lung metastasis (Cor = 0.882, P = 0.003), and lymph node metastasis (Spearman Cor = 0.410, P = 0.05). This evidence concerns the gene ERBB2 and metastatic malignant neoplasm in the lymph nodes.