For example, ChREBP has been shown to mediate the glucose induced expression of the thioredoxin‐interacting protein (TXNIP), which induces oxidative stress in pancreatic β cells [13]; and that the mTOR‐regulated ChREBP/TXNIP pathway plays an important role in inhibiting diabetes stress in β cells for cell survival [14]. Here, TXNIP is linked to diabetes mellitus.