We asked whether the combination of CHIP and age acceleration could further stratify carriers of CHIP into high‐risk and low‐risk groups for these outcomes using Cox proportional hazards models adjusted for chronological age at blood draw, low‐density lipoprotein cholesterol, high‐density lipoprotein cholesterol, triglycerides, systolic blood pressure, type 2 diabetes status, smoking status, and self‐reported ancestry in 4088 persons from JHS, FHS, and WHI (Figure 2B,C). This evidence concerns the gene STUB1 and type 2 diabetes mellitus.