LDHC mRNA and protein expression was significantly reduced in all cell lines using LDHC‐specific shRNA, albeit at different efficiencies, with the highest knockdown of LDHC in MDA‐MB‐468 and HCC‐1500 and to a lesser extent in MDA‐MB‐231 and BT‐549 (Fig. 1D). Here, LDHC is linked to hepatocellular carcinoma.