For i.v. injection of Sirpα−/− BMDMs into tumor-bearing WT mice, we first monitored the recruitment of fluorescently labeled BMDMs (GFP+) into engrafted MC38 tumors and found that when 1×107 BMDMs (GFP+) per mouse were injected, they comprised nearly 40% of the total number of intratumoral macrophages (Fig. 2g). The gene discussed is SIRPA; the disease is neoplasm.