Infection with either of the four strains resulted in an up-regulation of IL-6, IL-10, IFN-λ, IFN-γ, IP-10, MX-2, and TNF-α expression in the range of 10- to 1000-fold compared to non-infected hamsters (Fig. 4, Fig. S4, Supplementary Table S3). The gene discussed is IL10; the disease is infection.