No significantdifferences were found in the size of the major constituents of extracellular matrix(Figure 7); fibroblastsand their subcellular synthetic organelles (Supplementary material online,FigureS5); or features of elastin damage (Supplementary material online,FigureS6) between SCAD cases and HV. The gene discussed is ELN; the disease is spontaneous coronary artery dissection.