Comparison of the studied parameters in T-ALL with low TLE1 expression and T-ALL subgroup with high expression; the analysis showed that the low TEL1 gene expression was significantly associated with higher frequency CNS infiltration, non-remission and higher relapse rate (P < 0.001, < 0.001 and 0.023 respectively). The gene discussed is TLE1; the disease is acute lymphoblastic leukemia.