ETV6 and acute lymphoblastic leukemia: Chromosomal aberrations are characteristic in ALL, but are not sufficient to generate leukemia such as t(12; 21) (ETV6-RUNX1), t (1;19) (TCF3-PBX1), t (9;22) [BCR-ABL1 (Philadelphia)] and rearrangement of MLL (Mullighan et al., 2009).