Regarding the disease related parameters, TERT SNV rs 2242652 AA was associated a significant reduction in mean hemoglobin concentration, lower WBCs and platelets count, pancytopenia (88%), poor risk cytogenetics (92%), MDS with excess blasts (88%), MDS with multilineage dysplasia (12%), and high /very high IPSS-R score (Figures 3, 4). The gene discussed is TERT; the disease is myelodysplastic syndrome.