Analysis of the differences in frequency distributions of genotypes and alleles between cases and controls showed that TERT mutations were associated with a significantly increased risk of MDS; Odds ratios were significant for both the genotype distribution (2.6 for genotype GA, 6.4 for genotype AA) and for the allele distribution (1.7 for A) as shown in Figure 1. This evidence concerns the gene TERT and myelodysplastic syndrome.