Purified exosomes, obtained from supernatant of the immortalized ovarian epithelial cell line (IOSE‐80) and ovarian cancer cell lines (SKOV3 and A2780), showed nanovesicles with typical round or cup shape appearance and an average size around 30–150 nm of diameter under transmission electron microscopy (Figure 1A), and expressed positive exosomal markers as CD63 and HSP70 (Figure 1B). The gene discussed is CD63; the disease is ovarian cancer.