To investigate whether incorporation of the COMMD10 expression into the clinicpathologic variables of BCLC system would improve its predictive accuracy, we firstly performed univariate analysis and found various prognosis factors for OS in the NF training cohort, such as age, tumor size, albumin (ALB), tumor embolus, tumor differentiation, and COMMD10 (Table S3). The gene discussed is ALB; the disease is neoplasm.