For example, MiR‐3470b promotes bovine ephemeral fever virus replication via directly targeting MAVS, and miR‐27a inhibits MAVS expression, promoting the replication of vesicular stomatitis virus (VSV).[11, 12] Recent studies demonstrated that post‐transcriptional regulation of mRNA, such as m6A or 5‐methylcytosine (m5C) modifications, help cells respond more rapidly to external signaling at the transcriptional level.[13, 14, 15] However, the molecular regulatory mechanism of post‐transcriptional modification on MAVS mRNA remains indistinct. This evidence concerns the gene MAVS and Fever.