The pyrimidine glucosides (vicine and convicine) lead to favism which is a blood disorder caused when fava beans are eaten by humans with genetic mutations of glucose-6-phosphate dehydrogenase (G6PD), leading to decreased G6PD activity and reduced ability of red blood cells (RBCs) to produce ATP and regenerate glutathione (25). This evidence concerns the gene G6PD and hematologic disorder.