This contrasts with cluster *211 (Supplementary Material S1) that also contains congenital muscular dystrophy and ankle flexion contracture, as well as ‘increased endomysial connective tissue’, but not macroglossia, the functions for this cluster being ‘focal adhesion’ (hsa04510) and ‘ECM proteoglycans’ (R-HSA-3000178) but not “protein O-linked mannosylation”. This evidence concerns the gene ALB and macroglossia.