The expression levels of HP1-γ (CBX3) in dedifferentiated liposarcoma, myxoid/round cell liposarcoma, myxofibrosarcoma, and pleomorphic liposarcoma were upregulated by 2.270, 2.803, 2.439, and 2.785, fold for the Barretina sarcoma database. This evidence concerns the gene CBX3 and sarcoma.