High expression levels of HP1-α (CBX5) were found in uterine corpus leiomyosarcoma, synovial sarcoma, pleomorphic liposarcoma, dedifferentiated liposarcoma, and fibrosarcoma, with fold-changes of 2.005, 3.713, 3.401, 2.018, and 2.673, respectively (Quade uterus database and Detwiller sarcoma database). Here, CBX5 is linked to leiomyosarcoma of the corpus uteri.