Of all the variables, BMI (P = 0.041; HR, 0.935; 95% CI: 0.877, 0.997), CEA level (P = 0.017; HR, 1.004; 95% CI: 1.002, 1.007), number of tumours (P =0.018; HR, 1.425; 95% CI: 1.061, 1.913), lymph node metastasis (P = 0.027; HR, 2.079; 95% CI: 1.087, 3.978), and preoperative chemotherapy (P = 0.010; HR, 0.536; 95% CI: 0.333, 0.863) were found to be significant risk factors affecting OS in the univariate analysis. The gene discussed is CEACAM5; the disease is metastatic malignant neoplasm in the lymph nodes.