where Etumora is the number of CD8+ cells within the tumor, T is the number of tumor cells, μBTEis the T-dependent rate at which effector cells enter the tumor compartment from the blood, Eblooda is the number of CD8+ cells in the blood, a EaTis the death rate of activated CD8+ in the tumor [estimated at 0.462/day (29)], c is the rate at which activated CD8+ are inactivated by T [estimated at 9.42 x 10-12 cells x day (27)];. This evidence concerns the gene CD8A and neoplasm.