Specifically, the expression of BHLHE41 was correlated with the expression of VWF and IGFBP3 alone, and the expression of ANGPTL4 at Stage I/II did not correlate with that of VWF and BHLHE41. There was no correlation between the expression of IGFBP3 and VWF. For NDUFA4L2, EGLN3, and CA9 expression, the values of the correlation coefficients were similar to those observed during tumor progression, i.e., R = 0.845 and 0.789, respectively. The gene discussed is IGFBP3; the disease is neoplasm.