In addition, the expression of NOTCH3 was found to be elevated in OC and closely correlated with the clinical stage, pathological grade, lymph node metastasis, drug-resistant recurrence and survival rate [83]. NOTCH3 promotes the malignant progression of OC through enhancement of tumor cell proliferation, stemness maintenance and apoptosis resistance [84]. The gene discussed is NOTCH3; the disease is neoplasm.