Logistic regression analysis revealed that cutoff level of insulin ≥22.7, TNF-α ≥3.9, AGEs ≥11.6, creatinine ≥1.1 were the significant predicting factors for DM-DD versus DM-N with AOR 13.8 (3.1–60.3), 4.9 (1.1–20.6), 6.9 (1.0–46.5) and 7.8 (1.2–49.9), respectively; p < 0.05. This evidence concerns the gene TNF and diabetes mellitus.