N-(1-carbamoyl-2-phenyl-ethyl) butyramide (FBA), a butyrate releasing compound, confers protection to mice from colitis induced by dextran sodium sulphate by suppressing neutrophils recruitment and subsequent release of pro-inflammatory molecules mediated by HDAC-9/NF-κB inhibition and peroxisome proliferator-activated receptor gamma (PPAR-γ) upregulation142. This evidence concerns the gene PPARG and colitis.